Hyperparathyroidism in Cats


It is a condition in which the blood has extremely high levels of parathyroid hormone (also known as parathormone or PTH), which is caused by an overactive parathyroid gland. It is sometimes referred to as hyperparathyroidism. Parathyroid hormone is a hormone that regulates calcium and phosphorus levels in the blood, causing calcium to be reabsorbed from bone and, as a result, increasing calcium levels in the blood. The parathyroid glands are small hormone-producing glands that are located on or near the thyroid glands. The thyroid and parathyroid glands are located side by side in the neck, close to the windpipe or trachea; the prefix para- refers to nearby or beside, and thyroid refers to the actual thyroid gland; the prefix para- refers to nearby or alongside.



Hyperparathyroidism is a condition in which a tumor in the parathyroid gland causes the production of excessive amounts of parathyroid hormone, resulting in elevated calcium levels in the blood (hypercalcemia).

Hyperparathyroidism is a condition that is associated with malnutrition and long-term (chronic) kidney impairment, and it is caused by a deficiency in calcium and vitamin D.

Primary hyperparathyroidism has no known genetic cause; nevertheless, its association with specific breeds suggests that it may have a hereditary basis in some cases, according to some researchers. Secondary hyperparathyroidism is a condition that can arise in conjunction with hereditary kidney disease (hereditary nephropathy), but it is not inherited on its own. It appears that Siamese cats are more susceptible to this ailment. Cats have an average lifespan of 13 years, with a range of 8 to 15 years in between.

Types and Symptoms:

-The majority of cats suffering from primary hyperparathyroidism do not show any signs of disease.
-Acute calcium overload
-Excessive urination
-Excessive thirst is a symptom.
-The presence of stones in the urethra (urethral obstruction).
-Insomnia and coma are possible side effects.

A veterinarian may be able to feel the presence of enlarged parathyroid glands in the neck.

-Nutritional secondary hyperparathyroidism is a type of malnutrition caused by a diet that contains too little calcium and vitamin D, or too much phosphorus, respectively.

-Fractures of the bones and poor overall health are sometimes associated with nutritional secondary hyperparathyroidism (NSH).


-Primary hyperparathyroidism is caused by a PTH-secreting tumor of the parathyroid gland; typically, only one gland is involved; malignant tumors of the parathyroid glands are extremely rare.

-Malnutrition, such as a lack of calcium and vitamin D in the food or an excess of phosphorus in the diet, has been associated to secondary hyperparathyroidism in several studies.

-It has been shown that long-term (chronic) renal disease is associated with secondary hyperparathyroidism. Owing to a deficiency in calcitriol (a hormone produced by the kidneys that regulates calcium levels and absorption in the intestines), calcium is excreted through the kidneys, and calcium absorption is reduced through the intestinal tract. This may also be due to phosphorus retention in the body.

-Secondary hyperparathyroidism is a condition in which the thyroid gland produces too much parathyroid hormone. Causing this condition is either a calcium or vitamin D shortage, or a long-term (chronic) kidney ailment.


If cancer is suspected as the cause of this illness, your veterinarian will seek for it first and foremost. In addition to rodenticides, additional possibilities will be studied, including renal failure and vitamin D overdose, both of which have been associated with the use of rodenticides. The presence of too much calcium in the bloodstream of cats is still another potential. Urine tests can be used to determine calcium and phosphate levels.

Chronic renal failure patients usually have normal serum ionized calcium levels, whereas those with intrinsic hyperparathyroidism or hypercalcemia associated with a malignancy have elevated levels. If your veterinarian suspects that your pet has kidney stones, he or she may undergo x-ray and ultrasound imaging of the parathyroid gland to determine whether or not a tumor is present. It’s possible that your veterinarian will need to perform surgery to explore the thyroid and parathyroid glands if none of these diagnostic tests indicate anything.


A typical course of treatment for primary hyperparathyroidism includes hospitalization and surgical surgery. Patients who are not in critical condition and who have secondary hyperparathyroidism, which can be caused by malnutrition or long-term (chronic) renal impairment, can receive outpatient treatment for this condition. It is possible that your veterinarian will prescribe calcium supplements to help maintain calcium levels in your pet’s blood and intestines. It is also possible that low-phosphorus diets will be advised for the treatment of secondary hyperparathyroidism, which is a condition induced by chronic kidney disease. Surgery is the most effective treatment for primary hyperparathyroidism, and it is commonly required for the initial diagnosis of the condition as well as for the management of the condition. In the event that a tumor is discovered, surgical excision of the tumor is usually the most effective therapeutic option available. It will be necessary to write prescriptions in accordance with the final diagnostic and treatment plan that has been established.


A cure for primary hyperparathyroidism is not yet available; however, secondary hyperparathyroidism caused by hunger can be avoided by following a well-balanced dietary regimen.

Managing and Living

When one or more parathyroid glnds are surgically removed for the treatment of primary hyperparathyroidism, patients often experience low calcium levels in the blood (hypocalcemia). This is especially true in patients with presurgical calcium values greater than 14 mg/d. Once or twice a day for at least one week following surgery, the serum calcium levels of your cat will be checked, and your veterinarian will schedule frequent blood tests to check on the status of your cat’s kidneys during this period.